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Results in Control and Optimization ; : 100115, 2022.
Article in English | ScienceDirect | ID: covidwho-1768504

ABSTRACT

In this paper, a mathematical model of the COVID-19 pandemic with lockdown that provides a more accurate representation of the infection rate has been analyzed. In this model, the total population is divided into six compartments: the susceptible class, lockdown class, exposed class, asymptomatic infected class, symptomatic infected class, and recovered class. The basic reproduction number (R0) is calculated using the next-generation matrix method and presented graphically based on different progression rates and effective contact rates of infective individuals. The COVID-19 epidemic model exhibits the disease-free equilibrium and endemic equilibrium. The local and global stability analysis has been done at the disease-free and endemic equilibrium based on R0. The stability analysis of the model shows that the disease-free equilibrium is both locally and globally stable when R0<1, and the endemic equilibrium is locally and globally stable when R0>1 under some conditions. A control strategy including vaccination and treatment has been studied on this pandemic model with an objective functional to minimize. Finally, numerical simulation of the COVID-19 outbreak in India is carried out using MATLAB, highlighting the usefulness of the COVID-19 pandemic model and its mathematical analysis.

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